Hsing-Pang, Hsieh: search on Z-Library

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1

Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents

Mei-Jung Lai, Jang-Yang Chang, Hsueh-Yun Lee, Ching-Chuan Kuo, Mei-Hsiang Lin, Hsing-Pang Hsieh, Chi-Yen Chang, Jian-Sung Wu, Su-Ying Wu, Kuang-Shing Shey, Jing-Ping Liou

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 368 KB

english, 2011

2

Antitubulin agents for the treatment of cancer – a medicinal chemistry update

Mahindroo, Neeraj, Liou, Jing-Ping, Chang, Jang-Yang, Hsieh, Hsing-Pang

Journal:

Expert Opinion on Therapeutic Patents

Year:

2006

Language:

english

File:

PDF, 712 KB

english, 2006

3

Facile Identification of Dual FLT3-Aurora A Inhibitors: A Computer-Guided Drug Design Approach

Chang Hsu, Yung, Ke, Yi-Yu, Shiao, Hui-Yi, Lee, Chieh-Chien, Lin, Wen-Hsing, Chen, Chun-Hwa, Yen, Kuei-Jung, Hsu, John T.-A., Chang, Chungming, Hsieh, Hsing-Pang

Journal:

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

4

Antiviral Drug Discovery Against SARS-CoV

Wu, Yu-Shan, Lin, Wen-Hsing, T.-A.Hsu, John, Hsieh, Hsing-Pang

Journal:

Current Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

5

Discovery of a Novel Family of SARS-CoV Protease Inhibitors by Virtual Screening and 3D-QSAR Studies

Tsai, Keng-Chang, Chen, Shih-Yuan, Liang, Po-Huang, Lu, I-Lin, Mahindroo, Neeraj, Hsieh, Hsing-Pang, Chao, Yu-Sheng, Liu, Lincoln, Liu, Donald, Lien, Wei, Lin, Thy-Hou, Wu, Su-Ying

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

6

Discovery of 4-Amino and 4-Hydroxy-1-aroylindoles as Potent Tubulin Polymerization Inhibitors

Liou, Jing-Ping, Wu, Zi-Yi, Kuo, Ching-Chuan, Chang, Chi-Yen, Lu, Pei-Yi, Chen, Chi-Ming, Hsieh, Hsing-Pang, Chang, Jang-Yang

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 137 KB

english, 2008

7

A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors

Wen-Hsing Lin, Jen-Shin Song, Teng-Yuan Chang, Chun-Yu Chang, Yu-Ning Fu, Chi-Ling Yeh, Szu-Huei Wu, Yu-Wen Huang, Ming-Yu Fang, Tzu-Wen Lien, Hsing-Pang Hsieh, Yu-Sheng Chao, Shiu-Feng Huang, Shih-Fe

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 291 KB

english, 2008

8

Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study

Yi-Wei Chang, Wei-Cheng Chen, Ke-Ta Lin, Ling Chang, Hsien-Tsung Yao, Hsing-Pang Hsieh, Shih-Jung Lan, Chiung-Tong Chen, Yu-Sheng Chao, Teng-Kuang Yeh

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 438 KB

english, 2007

9

Facile solid phase synthesis of octreotide analogs using p-carboxybenzaldehyde as a novel linker to anchor Fmoc-threoninol to solid phase resins

Ying-Ta Wu, Hsing-Pang Hsieh, Chi-Yu Wu, Hui-Ming Yu, Shui-Tein Chen, Kung-Tsung Wang

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 138 KB

english, 1998

10

Direct solid-phase synthesis of octreotide conjugates: precursors for use as tumor-targeted radiopharmaceuticals

Hsing-Pang Hsieh, Ying-Ta Wu, Shui-Tein Chen, Kung-Tsung Wang

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 235 KB

english, 1999

11

Anaplastic lymphoma kinase (ALK) inhibitors: a review of design and discovery

Wang, Wen-Chieh, Shiao, Hui-Yi, Lee, Chieh-Chien, Fung, Ka-Shu, Hsieh, Hsing-Pang

Journal:

Year:

2014

Language:

english

File:

PDF, 848 KB

english, 2014

12

Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification

Ke, Yi-Yu, Singh, Vivek Kumar, Coumar, Mohane Selvaraj, Hsu, Yung Chang, Wang, Wen-Chieh, Song, Jen-Shin, Chen, Chun-Hwa, Lin, Wen-Hsing, Wu, Szu-Huei, Hsu, John T. A., Shih, Chuan, Hsieh, Hsing-Pang

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

13

Cover Picture: Facile Identification of Dual FLT3-Aurora A Inhibitors: A Computer-Guided Drug Design Approach (ChemMedChem 5/2014)

Chang Hsu, Yung, Ke, Yi-Yu, Shiao, Hui-Yi, Lee, Chieh-Chien, Lin, Wen-Hsing, Chen, Chun-Hwa, Yen, Kuei-Jung, Hsu, John T.-A., Chang, Chungming, Hsieh, Hsing-Pang

Journal:

Year:

2014

Language:

english

File:

PDF, 758 KB

english, 2014

14

Parallel Screening of Wild-Type and Drug-Resistant Targets for Anti-Resistance Neuraminidase Inhibitors

Hsu, Kai-Cheng, Hung, Hui-Chen, Horng, Jim-Tong, Fang, Ming-Yu, Chang, Chun-Yu, Li, Ling-Ting, Chen, I-Jung, Chen, Yun-Chu, Chou, Ding-Li, Chang, Chun-Wei, Hsieh, Hsing-Pang, Yang, Jinn-Moon, Hsu, Joh

Journal:

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

15

Structural Effects in Novel Steroidal Polyamine-DNA Binding

Hsieh, Hsing-Pang, Muller, James G., Burrows, Cynthia J.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 302 KB

english, 1994

16

Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer

Lee, Chieh-Chien, Shiao, Hui-Yi, Wang, Wen-Chieh, Hsieh, Hsing-Pang

Journal:

Expert Opinion on Investigational Drugs

Year:

2014

Language:

english

File:

PDF, 496 KB

english, 2014

17

Structure—Activity and Crystallographic Analysis of Benzophenone Derivatives — The Potential Anticancer Agents.

Hsing-Pang Hsieh, et al. et al.

Journal:

Year:

2003

File:

PDF, 18 KB

2003

18

Design and Synthesis of α-Ketoamides as Cathepsin S Inhibitors with Potential Applications against Tumor Invasion and Angiogenesis

Chen, Jo-Chun, Uang, Biing-Jiun, Lyu, Ping-Chiang, Chang, Jang-Yang, Liu, Ko-Jiunn, Kuo, Ching-Chuan, Hsieh, Hsing-Pang, Wang, Hsin-Chieh, Cheng, Chao-Sheng, Chang, Yi-Hsun, Chang, Margaret Dah-Tsyr,

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.47 MB

english, 2010

19

Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening

Chandar Charles, M.Ramya, Mahesh, Arun, Lin, Shu-Yu, Hsieh, Hsing-Pang, Dhayalan, Arunkumar, Coumar, Mohane Selvaraj

Journal:

Year:

2019

Language:

english

File:

PDF, 45.53 MB

english, 2019

20

Substituent Effects on Di-π-methane and Aza-di-π-methane Rearrangements of Dibenzo[f,h]quinoxalinobarrelenes.

Sheng-Yunn Lin, Hsing-Pang Hsieh, Rama Krishna Peddinti, Chun-Chen Liao

Journal:

Year:

2004

File:

PDF, 100 KB

2004

21

Synthesis and Structure–Activity Relationships of 1-Benzyl-4,5,6-trimethoxyindoles as a Novel Class of Potent Antimitotic Agents

Mei-Jung Lai, Ching-Chuan Kuo, Teng-Kuang Yeh, Hsing-Pang Hsieh, Li-Tzong Chen, Wen-Yu Pan, Kuang-Yang Hsu, Jang-Yang Chang, Jing-Ping Liou

Journal:

Year:

2009

Language:

english

File:

PDF, 241 KB

english, 2009

22

Generation of Ligand-Based Pharmacophore Model and Virtual Screening for Identification of Novel Tubulin Inhibitors with Potent Anticancer Activity

Chiang, Yi-Kun, Kuo, Ching-Chuan, Wu, Yu-Shan, Chen, Chung-Tong, Coumar, Mohane Selvaraj, Wu, Jian-Sung, Hsieh, Hsing-Pang, Chang, Chi-Yen, Jseng, Huan-Yi, Wu, Ming-Hsine

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 4.44 MB

english, 2009

23

Aurintricarboxylic acid inhibits influenza virus neuraminidase

Hui-Chen Hung, Ching-Ping Tseng, Jinn-Moon Yang, Yi-Wei Ju, Sung-Nain Tseng, Yen-Fu Chen, Yu-Sheng Chao, Hsing-Pang Hsieh, Shin-Ru Shih, John T.-A. Hsu

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 799 KB

english, 2009

24

Down-regulation of Survivin enhances sensitivity to BPR0L075 in human cancer cells via caspase-independent mechanisms

Cheung, Chun Hei Antonio, Kuo, Ching-Chuan, Chang, Chi-Yen, Coumar, Mohane Selvaraj, Hsieh, Hsing-Pang, Chang, Jang-Yang

Journal:

Nature Precedings

Year:

2008

File:

PDF, 1010 KB

2008

25

A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells

Shin-Hun Juang, Wen-Yu Pan, Ching-Chuan Kuo, Jing-Ping Liou, Yi-Mei Hung, Li-Tzong Chen, Hsing-Pang Hsieh, Jang-Yang Chang

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 433 KB

english, 2004

26

Synthesis and Structure−Activity Relationships of 3-Aminobenzophenones as Antimitotic Agents

Liou, Jing-Ping, Chang, Jang-Yang, Chang, Chun-Wei, Chang, Chi-Yen, Mahindroo, Neeraj, Kuo, Fu-Ming, Hsieh, Hsing-Pang

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

27

Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease

Lu, I-Lin, Mahindroo, Neeraj, Liang, Po-Huang, Peng, Yi-Hui, Kuo, Chih-Jung, Tsai, Keng-Chang, Hsieh, Hsing-Pang, Chao, Yu-Sheng, Wu, Su-Ying

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 389 KB

english, 2006

28

Strategies of Development of Antiviral Agents Directed Against Influenza Virus Replication

Hsieh, Hsing-Pang, Hsu, John

Journal:

Current Pharmaceutical Design

Year:

2007

Language:

english

File:

PDF, 419 KB

english, 2007

29

Syntheses of Two Pyridine C-Nucleosides as "Deletion-Modified" Analogs of dT and dC

Hsieh, Hsing-Pang, McLaughlin, Larry W.

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 548 KB

english, 1995

30

Synthesis and Structure−Activity Relationship of 2-Aminobenzophenone Derivatives as Antimitotic Agents

Liou, Jing-Ping, Chang, Chun-Wei, Song, Jeng-Shin, Yang, Yung-Ning, Yeh, Ching-Fang, Tseng, Huan-Yi, Lo, Yu-Kang, Chang, Yi-Ling, Chang, Chung-Ming, Hsieh, Hsing-Pang

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 82 KB

english, 2002

31

Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells

Chia-Nan Chen, Hsin-Hsiu Huang, Chia-Li Wu, Coney P.C. Lin, John T.A. Hsu, Hsing-Pang Hsieh, Shuang-En Chuang, Gi-Ming Lai

Journal:

Year:

2007

Language:

english

File:

PDF, 896 KB

english, 2007

32

Direct Solid Phase Synthesis of Biologically Active Peptide Alcohols

Wu, Ying-Ta, Hsieh, Hsing-Pang, Chen, Shui-Tein, Wang, Kung-Tsung

Journal:

Journal of the Chinese Chemical Society

Year:

1999

Language:

english

File:

PDF, 328 KB

english, 1999

33

Design of Drug-like Hepsin Inhibitors against Prostate Cancer and Kidney Stones

Blay, Vincent, Li, Mu-Chun, Ho, Sunita P., Stoller, Mashall L., Hsieh, Hsing-Pang, Houston, Douglas R.

Journal:

Acta Pharmaceutica Sinica B

Year:

2019

Language:

english

File:

PDF, 2.91 MB

english, 2019

34

Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors

Ting-Yueh Tsai, Mohane Selvaraj Coumar, Tsu Hsu, Hsing-Pang Hsieh, Chia-Hui Chien, Chiung-Tong Chen, Chung-Nien Chang, Yu-Kang Lo, Ssu-Hui Wu, Chung-Yu Huang, Yu-Wen Huang, Min-Hsien Wang, Hsin-Yi Wu,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

35

Structure–activity and crystallographic analysis of benzophenone derivatives—the potential anticancer agents

Hsing-Pang Hsieh, Jing-Ping Liou, Ying-Ting Lin, Neeraj Mahindroo, Jang-Yang Chang, Yung-Ning Yang, Shuenn-Shing Chern, Uan-Kang Tan, Chun-Wei Chang, Tung-Wei Chen, Chi-Hung Lin, Ying-Ying Chang, Chiu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

36

Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV

John T.-A. Hsu, Chih-Jung Kuo, Hsing-Pang Hsieh, Yeau-Ching Wang, Kuo-Kuei Huang, Coney P.-C. Lin, Ping-Fang Huang, Xin Chen, Po-Huang Liang

Journal:

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

37

A Novel Aurora-A Inhibitor, BPR1K0609S1, Sensitizes Colorectal Tumor cells to 5-Fluorofracil (5-FU) Treatment

Shionome, Yoshimi, Lin, Wen-Hsing, Shiao, Hui-Yi, Hsieh, Hsing-Pang, Hsu, John Tsu-An, Ouchi, Toru

Journal:

International Journal of Biological Sciences

Year:

2013

File:

PDF, 127 KB

2013

38

Aurora kinase inhibitor patents and agents in clinical testing: an update (2009 – 10) : This article is an update to aurora kinase inhibitors review, which appeared in: 2009, 19, 1-36 and 2009, 18, 1-20.

Cheung, Chun Hei Antonio, Coumar, Mohane Selvaraj, Chang, Jang-Yang, Hsieh, Hsing-Pang

Journal:

Expert Opinion on Therapeutic Patents

Year:

2011

Language:

english

File:

PDF, 2.87 MB

english, 2011

39

An Efficient, Mild and Scalable Synthesis of Bioactive Compounds Containing the Angelicin Scaffold

Shiao Hui-Yi, Kuo Ching-Chuan, Horng Jim-Tong, Shih Shin-Ru, Chang Sui-Yuan, Liao Chun-Chen, Hsu John T.-A., Amancha Prashanth Kumar, Chao Yu-Sheng, Hsieh Hsing-Pang

Journal:

Journal of the Chinese Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

40

Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold

Mohane Selvaraj Coumar, Jian-Sung Wu, Jiun-Shyang Leou, Uan-Kang Tan, Chung-Yu Chang, Teng-Yuan Chang, Wen-Hsing Lin, John T.-A. Hsu, Yu-Sheng Chao, Su-Ying Wu, Hsing-Pang Hsieh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 442 KB

english, 2008

41

Drug repurposing for chronic myeloid leukemia: in silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors

Singh, Vivek Kumar, Chang, Hsin-Huei, Kuo, Ching-Chuan, Shiao, Hui-Yi, Hsieh, Hsing-Pang, Coumar, Mohane Selvaraj

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2016

Language:

english

File:

PDF, 3.01 MB

english, 2016

42

A novel peroxisome proliferator-activated receptor α/γ agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells

Kao, Yu-Hsun, Hsieh, Hsing-Pang, Chitlimalla, Santhosh Kumar, Pan, Wen-Yu, Kuo, Ching-Chuan, Tsai, Yuan-Chin, Lin, Wen-Hsing, Chuang, Shuang-En, Chang, Jang-Yang

Journal:

Anti-Cancer Drugs

Year:

2008

Language:

english

File:

PDF, 179 KB

english, 2008

43

A selective Aurora-A 5′-UTR siRNA inhibits tumor growth and metastasis

Lai, Chien-Hsien, Chen, Ruo-Yu, Hsieh, Hsing-Pang, Tsai, Shaw-Jenq, Chang, Kung-Chao, Yen, Chia-Jui, Huang, Yu-Chuan, Liu, Yao-Wen, Lee, Jenq-Chang, Lai, Yi-Chien, Hung, Liang-Yi, Lin, Bo-Wen

Journal:

Year:

2020

File:

PDF, 3.47 MB

2020

44

Reactions of 2-hydroxybenzophenones with Corey–Chaykovsky reagent

Santhosh Kumar Chittimalla, Tsung-Che Chang, Ting-Chun Liu, Hsing-Pang Hsieh, Chun-Chen Liao

Journal:

Year:

2008

Language:

english

File:

PDF, 458 KB

english, 2008

45

Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities

Lu, I-Lin, Huang, Chien-Fu, Peng, Yi-Hui, Lin, Ying-Ting, Hsieh, Hsing-Pang, Chen, Chiung-Tong, Lien, Tzu-Wen, Lee, Hwei-Jen, Mahindroo, Neeraj, Prakash, Ekambaranellore, Yueh, Andrew, Chen, Hsin-Yi,

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

46

First Total Syntheses of (±)-Annuionone B and (±)-Tanarifuranonol

Shiao, Hui-Yi, Hsieh, Hsing-Pang, Liao, Chun-Chen

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 112 KB

english, 2008

47

Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: a molecular dynamics study

M, Ramya Chandar Charles, Hsieh, Hsing-Pang, Coumar, Mohane Selvaraj

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2018

Language:

english

File:

PDF, 1.94 MB

english, 2018

48

Bioassay-guided purification and identification of PPARα/γ agonists from Chlorella sorokiniana

Yu-Cheng Chou, Ekambaranellore Prakash, Chien-Fu Huang, Tzu-Wen Lien, Xin Chen, Ih-Jen Su, Yu-Sheng Chao, Hsing-Pang Hsieh, John Tsu-An Hsu

Journal:

Phytotherapy Research

Year:

2008

Language:

english

File:

PDF, 743 KB

english, 2008

49

4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents

Liou, Jing-Ping, Wu, Chang-Ying, Hsieh, Hsing-Pang, Chang, Chi-Yen, Chen, Chi-Ming, Kuo, Ching-Chuan, Chang, Jang-Yang

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

50

Biomimetic Syntheses of (±)-Isopalhinine A, (±)-Palhinine A, and (±)-Palhinine D

Chen, Chih-Ming, Shiao, Hui-Yi, Uang, Biing-Jiun, Hsieh, Hsing-Pang

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

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